Thomas Jefferson University: An Unexpected, & Novel, Target for Prostate Cancer – Our Biological Clock by admin_63069 | Feb 23, 2021 | News You Can Use Studies have shown that when circadian rhythms are disturbed through sleep deprivation, jet lag, or shift work, there is an increased incidence of some cancers including prostate cancer, which is the second leading cause of cancer death for men in the U.S.